Ischemia-Reperfusion (IR) results from blood flow through the ischemic area, also known as reperfusion injury. It is a common complication seen in ischemic organs after they are rescued from prolonged ischemia such as heart attack and stroke. 

The renal artery will be occluded unilaterally or bilaterally, followed by 24 hours of reperfusion. This will result in renal ischemia-reperfusion injury.