Leading Cardiovascular CRO in Preclinical Studies
Animal Models
Heart Failure with Preserved EF
- Why come to us?
Expertise: Our team excels in contract cardiovascular research, seasoned professionals with extensive experience and specialized knowledge in preclinical studies. Clients benefit from our proven track record of delivering high-quality results.
Customized Solutions: Recognizing the uniqueness of each research project, we prioritize customization in our services to meet the distinct needs and objectives of our clients. We collaborate closely with clients to develop personalized strategies.
Regulatory Compliance and Quality Assurance: Compliance with regulatory standards and maintaining stringent quality control are fundamental aspects of our approach to contract cardiovascular research in preclinical studies.
200
Completed Projects & Studies
5
Companies of Top 10 Largest Pharma
30
Countries & States Clients from
CL Laboratory is an AAALAC accredited institution
Post-MI Remodeling
To develop effective treatment of heart failure, rodent post-MI remodeling is the most commonly used animal model. This animal imitates the pathophysiology of human post- MI ventricular remodeling and heart failure.
Transverse Aortic Constriction (TAC)
Cardiac hypertrophy in animal models is can be induced by placing a band at the transverse aortic arch. Depending on the severity of the constriction, cardiac function can be compensatory at the early phase.
Pulmonary Artery Banding (PAB)
The PAB animal model can be induced by placing a band at the pulmonary trunk. This leads to right ventricular overload and hypertrophy.
What our customers say about us
Ryan M. Fryer, PhD
Boehringer Ingelheim Pharma
Rafe Shellooe, PhD
Plexxicon Inc.
“I really appreciate your thorough and detailed execution of the study from start to finish. I am very happy with your service and will be glad to refer others to you.”
