Gene and cell therapy

Transgenic mice and MI mice are common animal models used for gene and cell therapies. Without treatments, the transgenic mice and MI mice will develop heart failure. Viral vectors carrying therapeutic genetic material such as a working gene are delivered into cells through the blood stream or local injection.

 

 Post-Myocardial Infarction (MI) Remodeling Mouse Model. The left heart in each image shows a SHAM mouse and the right heart shows a mouse that underwent MI surgery.